Your Frame was showing art yesterday. Today you switch to the console or cable box and get a black screen with "No Signal" drifting across it. The art still loads, the menus still work, but the HDMI input is dead. That combination is good news, oddly enough. It usually means the panel is fine and the trouble is in the link between your device and the box behind your media console.
The Frame doesn't connect to your gear the way a normal TV does. Every HDMI port lives on a separate One Connect Box, and one thin white cable (Samsung calls it the Invisible Connection) carries the whole signal from that box up to the screen. So when an input drops, you have two extra links to check that a regular TV simply doesn't have.
Try this first
Confirm you're actually on the right input. Press Source and step through each HDMI slot one at a time. It's easy to land on HDMI 2 when the device is plugged into HDMI 1, and that looks exactly like a real fault.
Next, reseat the cable at the One Connect Box. Pull the HDMI plug for your device out of the box, wait a few seconds, and push it back until it clicks. Do the same at the device end. A plug that's a hair loose reads as no signal.
If that doesn't fix it, power-cycle the whole chain properly. Turn the TV off, then unplug both the TV and the One Connect Box from the wall, and unplug the source device too. Leave everything off for at least 30 seconds (a full minute is better) so the HDMI handshake clears completely. Power the One Connect Box and TV back on first, wait for the home screen, then turn the source device on last. Startup order matters more than it should here.
Reset the handshake, then ease off the demands
If the input flickers in and out, the two devices are failing to agree on a signal. Set your source to something conservative while you test: 4K at 60Hz, plain HDR or SDR, with Game features off. Once you get a stable picture you can step settings back up.
On a console or PC, switch off VRR and ALLM temporarily. Those features renegotiate the HDMI link and can trip a borderline connection into a black screen. One accuracy note worth knowing: The Frame handles HDR10 and HDR10+, not Dolby Vision. If a streamer or player is forcing Dolby Vision out, set it to HDR10+ instead so the handshake has something The Frame can accept.
Check the One Connect Box and its cable
Walk over to the One Connect Box and look for its standby light. No light at all means the box itself isn't getting power, so check its own cord before you blame the TV.
Then inspect the Invisible Connection cable. It's genuinely delicate. If it's been run under a heavy console foot, stapled to the wall, kinked behind a mount, or bent at a sharp angle during a move, the conductors inside can break while the jacket still looks perfect. A cable that's failing this way often shows as intermittent signal that comes and goes when you nudge the TV. Reseat both ends of it (one plugs into the box, one into the panel) and route it with gentle curves only.
Settings that trip up The Frame
Two menu items cause a lot of these calls. First, Anynet+ (HDMI-CEC): go to Settings, General, External Device Manager, and toggle Anynet+ off, then restart the TV and try the input. CEC squabbles between a receiver, a soundbar, and the TV can blank an input.
Second, Input Signal Plus. The Frame ships with this off on some ports, and without it a 4K device negotiates down or drops out entirely. Under External Device Manager, open Input Signal Plus and enable it for the specific HDMI port your device uses. Give the box a few seconds to relink after you do.
When it's the cable, not you
If a known-good Ultra High Speed cable, a confirmed input, a clean power-cycle, and those two settings still leave you staring at "No Signal," the failure is usually hardware. The most common culprit on The Frame is that fragile Invisible Connection cable, which is a replaceable part. Less often it's the One Connect Box or a single dead port, in which case test your device on a different HDMI slot to confirm.
Before you order anything, note exactly which devices, ports, and cables work and which don't. That short list is what Samsung support will ask for, and The Frame carries a one-year warranty on parts, so check your purchase date first. If three ports work and one is dead, you've found a port fault. If every input is gone but the art and menus are fine, look hard at that white cable.